Glaucoma

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Glaucoma November 2024

Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study

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Akiko Hanyuda; Yoshihiko Raita; Takahiro Ninomiya; Kazuki Hashimoto; Naoko Takada; Kota Sato; Jin Inoue; Seizo Koshiba; Gen Tamiya; Akira Narita; Masato Akiyama; Kazuko Omodaka; Satoru Tsuda; Yu Yokoyama; Noriko Himori; Yasuko Yamamoto; Takazumi Taniguchi; Kazuno Negishi; Toru Nakazawa
TAGS: glaucoma, metabolomics, open-angle glaucoma, multiomics, metabolites
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):44. https://doi.org/10.1167/iovs.65.13.44

Includes: Supplemental Content

Glaucoma November 2024

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

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Sarah E. Quillen; Elizabeth C. Kimball; Kelsey A. Ritter-Gordy; Liya Du; Zhuochen Yuan; Mary E. Pease; Salaheddine Madhoun; Thao D. Nguyen; Thomas V. Johnson; Harry A. Quigley; Ian F. Pitha
TAGS: astrocytes, did not receive therapy or drug, eye, glaucoma, mice, neuroprotection, optic nerve disorders, phosphotransferases, proteins, intraocular pressure
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):43. https://doi.org/10.1167/iovs.65.13.43

Includes: Supplemental Content

Retinal Cell Biology November 2024

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

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Juliane Hammer; Paul Röppenack; Sarah Yousuf; Anja Machate; Marika Fischer; Stefan Hans; Michael Brand
TAGS: adult, zebrafish, phenotype, visual system, retina
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):42. https://doi.org/10.1167/iovs.65.13.42

Includes: Supplemental Content

Cornea November 2024

Restoration of Corneal Stiffness in Rabbits Following Withdrawal of Travoprost

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XiaoBo Zheng; Chong Wang; YiWen Fan; YuXin Hong; Han Bao; ErChi Zhang; Yi Jin; Peng Yang; LingQiao Li; JunJie Wang; ShiHao Chen; Ahmed Elsheikh; FangJun Bao
TAGS: cornea, oryctolagus cuniculus, travoprost, cardiac ct, multiple wake test, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):35. https://doi.org/10.1167/iovs.65.13.35

Glaucoma November 2024

Differentiating Multiple Sclerosis and Glaucoma With Sectoral Pattern Analysis of Peripapillary Nerve Fiber Layer

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Po-Han Yeh; Ou Tan; Elizabeth Silbermann; Elizabeth White; Dongseok Choi; Aiyin Chen; Eliesa Ing; Dennis Bourdette; Jie Wang; Yali Jia; David Huang
TAGS: eye, glaucoma, multiple sclerosis, nerve fibers
Trans. Vis. Sci. Tech.. 2024; 13(11):11. https://doi.org/10.1167/tvst.13.11.11

Glaucoma November 2024

Downregulation of SARM1 Protects Retinal Ganglion Cell Axonal and Somal Degeneration Via JNK Activation in a Glaucomatous Model of Ocular Hypertension

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Xuejin Zhang; Ting Li; Rong Zhang; Junfeng Li; Kaidi Wang; Jihong Wu
TAGS: axon, down-regulation, glaucoma, ocular hypertension, optic nerve, retina, retinal ganglion cells, tissue degeneration, wounds and injuries, injections
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):7. https://doi.org/10.1167/iovs.65.13.7

Includes: Supplemental Content

Glaucoma November 2024

Progressive Optic Neuropathy in Hydrocephalic Ccdc13 Mutant Mice Caused by Impaired Axoplasmic Transport at the Optic Nerve Head

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Mingjuan Wu; Xinyi Zhao; Shanzhen Peng; Xiaoyu Zhang; Jiali Ru; Lijing Xie; Tao Wen; Yingchun Su; Shujuan Xu; Dianlei Guo; Jianmin Hu; Haotian Lin; Tiansen Li; Chunqiao Liu
TAGS: axonal transport, mice, optic disk, optic nerve, optic nerve disorders, axon, retina, hydrocephalus
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):5. https://doi.org/10.1167/iovs.65.13.5

Includes: Supplemental Content

Glaucoma November 2024

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult

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Manik Bansal; Bingrui Wang; Susannah Waxman; Fuqiang Zhong; Yi Hua; Yuankai Lu; Juan Reynaud; Brad Fortune; Ian A. Sigal
TAGS: axon, body tissue, intraocular pressure, optic disk, volume, reconstructive surgical procedures
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):1. https://doi.org/10.1167/iovs.65.13.1

Includes: Supplemental Content

Glaucoma October 2024

A Novel Approach To Predict Glaucomatous Impairment in the Central 10° Visual Field, Excluding the Effect of Cataract

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Ryo Tomita; Ryo Asaoka; Kazunori Hirasawa; Yuri Fujino; Tetsuro Omura; Tsutomu Inatomi; Akira Obana; Koji M. Nishiguchi; Masaki Tanito
TAGS: cataract, glaucoma, impairment, visual fields, maximum tolerated dose, preoperative care
Trans. Vis. Sci. Tech.. 2024; 13(10):35. https://doi.org/10.1167/tvst.13.10.35

Glaucoma October 2024

Trabecular Meshwork Abnormalities in a Model of Congenital Glaucoma Due to LTBP2 Mutation

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Odalys Torné; Kazuya Oikawa; Leandro B. C. Teixeira; Julie A. Kiland; Gillian J. McLellan
TAGS: cats, elastic fibers, glaucoma, congenital, mutation, trabecular meshwork, eye, shape, collagen
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):28. https://doi.org/10.1167/iovs.65.12.28

Includes: Supplemental Content

Letters to the Editor October 2024

Effect of Depth-Dependent Integrated Visual Field on Vision-Related Quality of Life in Glaucoma

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Mehrdad Gazanchian; Nomdo M. Jansonius
TAGS: glaucoma, quality of life, vision, visual fields
Trans. Vis. Sci. Tech.. 2024; 13(10):27. https://doi.org/10.1167/tvst.13.10.27

Clinical and Epidemiologic Research October 2024

Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort

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Zihan Sun; Kelsey V. Stuart; Robert N. Luben; Amy L. Auld; Nicholas G. Strouthidis; Peng T. Khaw; Hari Jayaram; Anthony P. Khawaja; Paul J. Foster; on behalf of the UK Biobank Eye and Vision Consortium
TAGS: air pollution, cohort studies, glaucoma, uk biobank
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):22. https://doi.org/10.1167/iovs.65.12.22

Includes: Supplemental Content

Artificial Intelligence October 2024

Automated Identification of Clinically Relevant Regions in Glaucoma OCT Reports Using Expert Eye Tracking Data and Deep Learning

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Ye Tian; Anurag Sharma; Shubh Mehta; Shubham Kaushal; Jeffrey M. Liebmann; George A. Cioffi; Kaveri A. Thakoor
TAGS: eye-tracking, glaucoma, deep learning, training
Trans. Vis. Sci. Tech.. 2024; 13(10):24. https://doi.org/10.1167/tvst.13.10.24

Glaucoma October 2024

Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements

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Hongli Yang; Juan Reynaud; Glen P. Sharpe; Dawn Jennings; Cindy Albert; Trinity Holthausen; Xiue Jiang; Shaban Demirel; Steven L. Mansberger; Marcelo T. Nicolela; Stuart K. Gardiner; Balwantray C. Chauhan; Claude F. Burgoyne; Brad Fortune
TAGS: eye, glaucoma, pixel
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):17. https://doi.org/10.1167/iovs.65.12.17

Includes: Supplemental Content

Glaucoma October 2024

DAMPs Drive Fibroinflammatory Changes in the Glaucomatous ONH

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Emma K. Geiduschek; Emma K. Bricco; Colleen M. McDowell
TAGS: glaucoma, mice, optic disk, eye, retinal nerve fiber layer
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):13. https://doi.org/10.1167/iovs.65.12.13

Includes: Supplemental Content

Retina October 2024

Critical Impact of Working Distance on OCT Imaging: Correction of Optical Distortion and Its Effects on Measuring Retinal Curvature

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Yong Woo Kim; Glen P. Sharpe; Julia Siber; Ralf Keßler; Jörg Fischer; Tilman Otto; Balwantray C. Chauhan
TAGS: diagnostic imaging, eye, optics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):10. https://doi.org/10.1167/iovs.65.12.10

Includes: Multimedia, Supplemental Content

Glaucoma October 2024

IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

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Yooree G. Chung; Shan Fan; Vikas Gulati; Hoi-Lam Li; Haiyan Gong; Carol B. Toris; Mark R. Prausnitz; C. Ross Ethier
TAGS: hydrogel, injections, intraocular pressure, eye, hypertension
Trans. Vis. Sci. Tech.. 2024; 13(10):14. https://doi.org/10.1167/tvst.13.10.14

Includes: Supplemental Content

Glaucoma October 2024

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats

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Lijuan Xu; Yin Zhao; Xinyao Zhang; Xiaorui Gang; Jialing Han; Tao Zhou; Binyan Qi; Shuning Song; Ruiyi Ren; Yuanbo Liang
TAGS: intraocular pressure, rats, fibrosis, eye, schlemm's canal, trabecular meshwork
Trans. Vis. Sci. Tech.. 2024; 13(10):10. https://doi.org/10.1167/tvst.13.10.10

Includes: Supplemental Content

Glaucoma October 2024

Characteristics of a Large Database of Healthy Eyes From Optometry Practices: Implications for a Real-World Reference Database

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Donald C. Hood; Mary Durbin; Sol La Bruna; Chris Lee; Yi Sing Hsiao; Nevin W. El-Nimri; Carlos Gustavo De Moraes; Emmanouil Tsamis
TAGS: eye, optometry, screening, reading (activity)
Trans. Vis. Sci. Tech.. 2024; 13(10):8. https://doi.org/10.1167/tvst.13.10.8

Includes: Supplemental Content

Glaucoma October 2024

Normative Profile of Retinal Nerve Fiber Layer Thickness and Lamina Cribrosa-Related Parameters in a Healthy Non-Glaucoma Cynomolgus Monkey Colony

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Jian Wu; Ruyue Li; Sirui Zhu; Kezhe Chen; Caixia Lin; Jiaxin Tian; Lijie Pan; Hongyi Liu; Xu Jia; Ziyu Yu; Zhidong Li; Yingting Zhu; Wei Liu; Chenlong Yang; Chiwai Wong; Ningli Wang; Yehong Zhuo; for the Non-Human Primate Eye Study Group
TAGS: glaucoma, macaca fascicularis, retinal nerve fiber layer, eye, cercopithecidae, intraocular pressure
Trans. Vis. Sci. Tech.. 2024; 13(10):6. https://doi.org/10.1167/tvst.13.10.6

Includes: Supplemental Content

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Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study

The Mechanisms of Neuroprotection by Topical Rho Kinase Inhibition in Experimental Mouse Glaucoma and Optic Neuropathy

Blind But Alive – Congenital Loss of atoh7 Disrupts the Visual System of Adult Zebrafish

Restoration of Corneal Stiffness in Rabbits Following Withdrawal of Travoprost

Differentiating Multiple Sclerosis and Glaucoma With Sectoral Pattern Analysis of Peripapillary Nerve Fiber Layer

Downregulation of SARM1 Protects Retinal Ganglion Cell Axonal and Somal Degeneration Via JNK Activation in a Glaucomatous Model of Ocular Hypertension

Progressive Optic Neuropathy in Hydrocephalic Ccdc13 Mutant Mice Caused by Impaired Axoplasmic Transport at the Optic Nerve Head

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult

A Novel Approach To Predict Glaucomatous Impairment in the Central 10° Visual Field, Excluding the Effect of Cataract

Trabecular Meshwork Abnormalities in a Model of Congenital Glaucoma Due to LTBP2 Mutation

Effect of Depth-Dependent Integrated Visual Field on Vision-Related Quality of Life in Glaucoma

Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort

Automated Identification of Clinically Relevant Regions in Glaucoma OCT Reports Using Expert Eye Tracking Data and Deep Learning

Diagnostic Performance for Detection of Glaucomatous Structural Damage Using Pixelwise Analysis of Retinal Thickness Measurements

DAMPs Drive Fibroinflammatory Changes in the Glaucomatous ONH

Critical Impact of Working Distance on OCT Imaging: Correction of Optical Distortion and Its Effects on Measuring Retinal Curvature

IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space

Low Intraocular Pressure Induces Fibrotic Changes in the Trabecular Meshwork and Schlemm's Canal of Sprague Dawley Rats

Characteristics of a Large Database of Healthy Eyes From Optometry Practices: Implications for a Real-World Reference Database

Normative Profile of Retinal Nerve Fiber Layer Thickness and Lamina Cribrosa-Related Parameters in a Healthy Non-Glaucoma Cynomolgus Monkey Colony

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