Retina

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Cornea November 2023

Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

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Dongyu Li; Xin Jin; Chao Wang; Nan Zhang; Di Jin; Hong Zhang
TAGS: cornea, diabetes mellitus, diabetes mellitus, type 2, microvessels, neurons, perfusion, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):44. https://doi.org/10.1167/iovs.64.14.44

Retina November 2023

Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration

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Aoife M. L. Hunter; Roger S. Anderson; Tony Redmond; David F. Garway-Heath; Pádraig J. Mulholland
TAGS: age-related macular degeneration, spatial summation, summation, temporal summation, visual fields, perimetry, significance
Trans. Vis. Sci. Tech.. 2023; 12(11):37. https://doi.org/10.1167/tvst.12.11.37

Retina November 2023

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

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Michael J. Huvard; Jennifer L. Patnaik; David M. Kleinman; Mary Preston; David N. Zacks; Andrew J. Kocab; Jana van de Goor; Brandie D. Wagner; Steve Cho; Anne M. Lynch; Naresh Mandava
TAGS: eye, macula lutea, retinal detachment, rhegmatogenous retinal detachment, surgical procedures, operative, vision
Trans. Vis. Sci. Tech.. 2023; 12(11):35. https://doi.org/10.1167/tvst.12.11.35

Includes: Supplemental Content

Research Opportunities November 2023

Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop

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S. Robert Levine; Martin G. Myers; Ryan Barunas; Dolly S. Chang; Sanjoy Dutta; Ted Maddess; Jeffrey M. Liebmann; Steve Sherman; Melvina Eydelman; Jennifer K. Sun; Wiley Chambers; Kerstin Wickström; Ulrich F. O. Luhmann; Martin Pallinat; Adam Glassman; Lloyd Paul Aiello; Dorene S. Markel; Thomas W. Gardner
TAGS: diabetes mellitus, retinal diseases, surrogate endpoints, vision
Trans. Vis. Sci. Tech.. 2023; 12(11):33. https://doi.org/10.1167/tvst.12.11.33

Includes: Supplemental Content

Retina November 2023

GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

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Yanlin Feng; Chenyang Hu; Kaixuan Cui; Matthew Fan; Wu Xiang; Dan Ye; Yuxun Shi; Huiwen Ye; Xue Bai; Yantao Wei; Yue Xu; Jingjing Huang
TAGS: ischemia, necroptosis, reperfusion therapy, wounds and injuries, physiologic reperfusion, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):42. https://doi.org/10.1167/iovs.64.14.42

Includes: Supplemental Content

Retinal Cell Biology November 2023

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

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Todd McLaughlin; Grant Wang; Andy Medina; Jacob Perkins; Rhudwan Nihlawi; Don Seyfried; Zihua Hu; Joshua J. Wang; Sarah X. Zhang
TAGS: diabetes mellitus, diabetic retinopathy, mice, personal integrity, photoreceptors, electroretinography, retina, synapses
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):40. https://doi.org/10.1167/iovs.64.14.40

Includes: Supplemental Content

Glaucoma November 2023

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

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Simon T. Gustavsson; Tim J. Enz; James R. Tribble; Mattias Nilsson; Anna Lindqvist; Christina Lindén; Anna Hagström; Carola Rutigliani; Emma Lardner; Gustav Stålhammar; Pete A. Williams; Gauti Jóhannesson
TAGS: glaucoma, niacinamide, ocular hypertension, retinal vasculature, vasculature, vascular flow, eye, optic disk
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):34. https://doi.org/10.1167/iovs.64.14.34

Includes: Supplemental Content

Retina November 2023

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

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Eric C. Spivey; Jinggang Yin; Edward Chaum; John P. Wikswo
TAGS: retinal pigment cell, vascular endothelial growth factor a, fluid flow, bodily secretions, hypoxia
Trans. Vis. Sci. Tech.. 2023; 12(11):28. https://doi.org/10.1167/tvst.12.11.28

Includes: Supplemental Content

Retina November 2023

Deep Learning–Facilitated Study of the Rate of Change in Photoreceptor Outer Segment Metrics in RPGR -Related X-Linked Retinitis Pigmentosa

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Yi-Zhong Wang; Katherine Juroch; Yineng Chen; Gui-Shuang Ying; David G. Birch
TAGS: deep learning, photoreceptors, retinitis pigmentosa, volume, x-linked inheritance, eye, baseline value, follow-up, disease progression
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):31. https://doi.org/10.1167/iovs.64.14.31

Retina November 2023

The Impact of Diabetic Retinopathy on the Choriocapillaris in Neovascular AMD

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Pasquale Viggiano; Alexandra Miere; Enrico Borrelli; Giacomo Boscia; Maria Oliva Grassi; Eric H. Souied; Giovanni Alessio; Francesco Boscia
TAGS: chief complaint, diabetic retinopathy, exudative age-related macular degeneration, eye, macular neovascularization, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):32. https://doi.org/10.1167/iovs.64.14.32

Physiology and Pharmacology November 2023

O-GlcNAcylation Inhibition Upregulates Connexin43 Expression in the Endothelium to Protect the Tight Junction Barrier in Diabetic Retinopathy

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Guodong Liu; Le Feng; Xiaoqiang Liu; Peng Gao; Fang Wang
TAGS: connexin 43, tight junctions, glucose, diabetic retinopathy
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):30. https://doi.org/10.1167/iovs.64.14.30

Includes: Supplemental Content

Anatomy and Pathology/Oncology November 2023

Next-Generation Sequencing of Vitreoretinal Lymphoma by Vitreous Liquid Biopsy: Diagnostic Potential and Genotype/Phenotype Correlation

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Jay Jiyong Kwak; Kwang Seob Lee; Junwon Lee; Yong Joon Kim; Eun Young Choi; Suk Ho Byeon; Won Seok Chang; Yu Ri Kim; Jin Seok Kim; Saeam Shin; Seung-Tae Lee; Sung Soo Kim; Christopher Seungkyu Lee
TAGS: biopsy, massively-parallel genome sequencing, primary vitreoretinal lymphoma, vitreous body, liquid biopsy, genotype-phenotype associations
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):27. https://doi.org/10.1167/iovs.64.14.27

Includes: Supplemental Content

Genetics November 2023

Clinical Characteristics and Genetic Variants in Taiwanese Patients With PROM1 -Related Inherited Retinal Disorders

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Tzu-Yi Lin; Pei-Liang Wu; Eugene Yu-Chuan Kang; Yi-Chun Chi; Laura A. Jenny; Pei-Hsuan Lin; Chia-Ying Lee; Chun-Hsiu Liu; Laura Liu; Lung-Kun Yeh; Kuan-Jen Chen; Yih-Shiou Hwang; Wei-Chi Wu; Chi-Chun Lai; Meng-Chang Hsiao; Pei-Kang Liu; Nan-Kai Wang
TAGS: electroretinography, genetics, retinal diseases, spectral domain-optical coherence tomography, taiwanese, fundus autofluorescence imaging, color, family, genes
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):25. https://doi.org/10.1167/iovs.64.14.25

Includes: Supplemental Content

Retina November 2023

Narrowing Ratio of Retinal Veins at Arteriovenous Crossing in Patients With Branch Retinal Vein Occlusion Versus That in Healthy Individuals

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Ryo Tomita; Kensuke Goto; Yoshitaka Ueno; Katsuya Yamaguchi; Jun Takeuchi; Tomohiko Akahori; Hiroki Kaneko; Takeshi Iwase
TAGS: central retinal vein, eye, venous retinal branch occlusion
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):22. https://doi.org/10.1167/iovs.64.14.22

Includes: Supplemental Content

Anatomy and Pathology/Oncology November 2023

Spontaneously Myopic Guinea Pig: Model of Early Pathologic Myopia

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Yue Zhang; Wenyu Tang; Jianqiang Liang; Xiangtian Zhou; Si Chen; Zhina Zhi
TAGS: caviidae, eye, guinea, myopia, myopic macular degeneration, vocal cord dysfunction, language morphology, morphology, refraction, sclera
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):19. https://doi.org/10.1167/iovs.64.14.19

Retina November 2023

Retinal Arteriolar Wall Remodeling in Diabetes Captured With AOSLO

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Kaitlyn A. Sapoznik; Thomas J. Gast; Alessandra Carmichael-Martins; Brittany R. Walker; Raymond L. Warner; Stephen A. Burns
TAGS: arteriole, diabetes mellitus, diabetes mellitus, type 2, diagnostic imaging
Trans. Vis. Sci. Tech.. 2023; 12(11):16. https://doi.org/10.1167/tvst.12.11.16

Clinical Trials November 2023

Effects of Spectacle Lenses With Aspherical Lenslets on Peripheral Eye Length and Peripheral Refraction in Myopic Children: A 2-Year Randomized Clinical Trial

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Yingying Huang; Jiali Zhang; Ziang Yin; Adeline Yang; Daniel P. Spiegel; Björn Drobe; Hao Chen; Jinhua Bao; Xue Li
TAGS: child, clinical trials, eye, lens (device), lens, crystalline, refraction, permissible exposure limit, myopia, retina
Trans. Vis. Sci. Tech.. 2023; 12(11):15. https://doi.org/10.1167/tvst.12.11.15

Retina November 2023

Cross-Platform Identification and Validation of Uveal Melanoma Vitreous Protein Biomarkers

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Gabriel Velez; Julian Wolf; Antoine Dufour; Prithvi Mruthyunjaya; Vinit B. Mahajan
TAGS: biological markers, intraocular melanoma, neoplasms, proteins, proteomics, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):14. https://doi.org/10.1167/iovs.64.14.14

Includes: Supplemental Content

Retina November 2023

Retinal Vascular Oxygen Saturation in a Sample of Chinese Myopic Adults

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Shanshan Ge; Yuehua Zhou; Chen Li; Mingxu Zhang
TAGS: adult, chinese (other dialects), chinese people, oxygen saturation measurement, myopia
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):13. https://doi.org/10.1167/iovs.64.14.13

Retina November 2023

Development of an Automated Electroretinography Analysis Approach

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Andrew J. Feola; Rachael S. Allen; Kyle C. Chesler; Machelle T. Pardue
TAGS: datasets, electroretinography, waveforms, verification
Trans. Vis. Sci. Tech.. 2023; 12(11):14. https://doi.org/10.1167/tvst.12.11.14

Includes: Supplemental Content

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Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop

GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

Deep Learning–Facilitated Study of the Rate of Change in Photoreceptor Outer Segment Metrics in RPGR -Related X-Linked Retinitis Pigmentosa

The Impact of Diabetic Retinopathy on the Choriocapillaris in Neovascular AMD

O-GlcNAcylation Inhibition Upregulates Connexin43 Expression in the Endothelium to Protect the Tight Junction Barrier in Diabetic Retinopathy

Next-Generation Sequencing of Vitreoretinal Lymphoma by Vitreous Liquid Biopsy: Diagnostic Potential and Genotype/Phenotype Correlation

Clinical Characteristics and Genetic Variants in Taiwanese Patients With PROM1 -Related Inherited Retinal Disorders

Narrowing Ratio of Retinal Veins at Arteriovenous Crossing in Patients With Branch Retinal Vein Occlusion Versus That in Healthy Individuals

Spontaneously Myopic Guinea Pig: Model of Early Pathologic Myopia

Retinal Arteriolar Wall Remodeling in Diabetes Captured With AOSLO

Effects of Spectacle Lenses With Aspherical Lenslets on Peripheral Eye Length and Peripheral Refraction in Myopic Children: A 2-Year Randomized Clinical Trial

Cross-Platform Identification and Validation of Uveal Melanoma Vitreous Protein Biomarkers

Retinal Vascular Oxygen Saturation in a Sample of Chinese Myopic Adults

Development of an Automated Electroretinography Analysis Approach

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