Eye Anatomy and Disorders

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Immunology and Microbiology November 2023

Too Much of a Good Thing: Extended Duration of Gut Microbiota Depletion Reverses Protection From Experimental Autoimmune Uveitis

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Ryan Salvador; Reiko Horai; Amy Zhang; Yingyos Jittayasothorn; Jihong Tang; Akriti Gupta; Vijayaraj Nagarajan; Rachel R. Caspi
TAGS: antibiotics, autoimmunity, mice, microbiome, uveitis, genes, rna, ribosomal, 16s, t-lymphocytes, immunization
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):43. https://doi.org/10.1167/iovs.64.14.43

Cornea November 2023

Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

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Dongyu Li; Xin Jin; Chao Wang; Nan Zhang; Di Jin; Hong Zhang
TAGS: cornea, diabetes mellitus, diabetes mellitus, type 2, microvessels, neurons, perfusion, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):44. https://doi.org/10.1167/iovs.64.14.44

Retina November 2023

Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration

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Aoife M. L. Hunter; Roger S. Anderson; Tony Redmond; David F. Garway-Heath; Pádraig J. Mulholland
TAGS: age-related macular degeneration, spatial summation, summation, temporal summation, visual fields, perimetry, significance
Trans. Vis. Sci. Tech.. 2023; 12(11):37. https://doi.org/10.1167/tvst.12.11.37

Retina November 2023

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

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Michael J. Huvard; Jennifer L. Patnaik; David M. Kleinman; Mary Preston; David N. Zacks; Andrew J. Kocab; Jana van de Goor; Brandie D. Wagner; Steve Cho; Anne M. Lynch; Naresh Mandava
TAGS: eye, macula lutea, retinal detachment, rhegmatogenous retinal detachment, surgical procedures, operative, vision
Trans. Vis. Sci. Tech.. 2023; 12(11):35. https://doi.org/10.1167/tvst.12.11.35

Includes: Supplemental Content

Cornea & External Disease November 2023

Diagnostic Potential of Anterior Segment Optical Coherence Tomography Scans for Pseudomonas Keratitis

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Haidar Khalil; Matthias Bolz; Klemens Waser; Leon Pomberger; Peter Laubichler; Paul Jirak; Nino Hirnschall
TAGS: infiltrates, keratitis, optical coherence tomography, pseudomonas, cornea, body tissue
Trans. Vis. Sci. Tech.. 2023; 12(11):34. https://doi.org/10.1167/tvst.12.11.34

Pediatric Ophthalmology & Strabismus November 2023

Social Determinants of Health in Pediatric Ophthalmology Patients: Availability of Data in the Electronic Health Record and Association With Clinic Attendance

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Omer Jamal; Ashwin Mallipatna; Stephen W. Hwang; Helen Dimaras
TAGS: electronic medical records, operating room, pediatric ophthalmology, social determinants of health, cohort studies, neighborhood
Trans. Vis. Sci. Tech.. 2023; 12(11):36. https://doi.org/10.1167/tvst.12.11.36

Includes: Supplemental Content

Research Opportunities November 2023

Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop

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S. Robert Levine; Martin G. Myers; Ryan Barunas; Dolly S. Chang; Sanjoy Dutta; Ted Maddess; Jeffrey M. Liebmann; Steve Sherman; Melvina Eydelman; Jennifer K. Sun; Wiley Chambers; Kerstin Wickström; Ulrich F. O. Luhmann; Martin Pallinat; Adam Glassman; Lloyd Paul Aiello; Dorene S. Markel; Thomas W. Gardner
TAGS: diabetes mellitus, retinal diseases, surrogate endpoints, vision
Trans. Vis. Sci. Tech.. 2023; 12(11):33. https://doi.org/10.1167/tvst.12.11.33

Includes: Supplemental Content

Cornea & External Disease November 2023

Biological and Adhesive Properties of an Autologous Protein-Based Fibrin Sealant for Ophthalmological Applications

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Eduardo Anitua; Francisco Muruzabal; Roberto Prado; Ander Pino; Roberto Tierno; Mairobi Persinal-Medina; Mohammad H. Alkhraisat; Jesús Merayo-Lloves
TAGS: adhesives, fibrin tissue adhesive, proteins, growth factor, adhesions
Trans. Vis. Sci. Tech.. 2023; 12(11):32. https://doi.org/10.1167/tvst.12.11.32

Glaucoma November 2023

Single- and Dual-Task Gait Performance in Patients With Open-Angle Glaucoma: A Cross-sectional Study

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Constantin W. Freitag; Martin Behrens; Thorben Menrad; Khaldoon O. Al-Nosairy; Francie H. Stolle; Gokulraj T. Prabhakaran; Rosalie Beyer; Hagen Thieme; Michael B. Hoffmann; Lutz Schega
TAGS: cross-sectional studies, gait, glaucoma, open-angle glaucoma
Trans. Vis. Sci. Tech.. 2023; 12(11):31. https://doi.org/10.1167/tvst.12.11.31

Retina November 2023

GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

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Yanlin Feng; Chenyang Hu; Kaixuan Cui; Matthew Fan; Wu Xiang; Dan Ye; Yuxun Shi; Huiwen Ye; Xue Bai; Yantao Wei; Yue Xu; Jingjing Huang
TAGS: ischemia, necroptosis, reperfusion therapy, wounds and injuries, physiologic reperfusion, retina
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):42. https://doi.org/10.1167/iovs.64.14.42

Includes: Supplemental Content

Immunology and Microbiology November 2023

Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence

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Tejabhiram Yadavalli; Chandrashekhar Patil; Pankaj Sharma; Ipsita Volety; Hemant Borase; Divya Kapoor; Deepak Shukla
TAGS: caviidae, guinea, human herpesvirus 1, infections, recurrence, keratitis, herpetic, cornea, oryctolagus cuniculus, pathology, viruses
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):41. https://doi.org/10.1167/iovs.64.14.41

Includes: Supplemental Content

Retinal Cell Biology November 2023

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

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Todd McLaughlin; Grant Wang; Andy Medina; Jacob Perkins; Rhudwan Nihlawi; Don Seyfried; Zihua Hu; Joshua J. Wang; Sarah X. Zhang
TAGS: diabetes mellitus, diabetic retinopathy, mice, personal integrity, photoreceptors, electroretinography, retina, synapses
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):40. https://doi.org/10.1167/iovs.64.14.40

Includes: Supplemental Content

Visual Neuroscience November 2023

Altered Perception of the Bistable Motion Quartet in Albinism

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Khaldoon O. Al-Nosairy; Elisabeth V. Quanz; Charlotta M. Eick; Michael B. Hoffmann; Jürgen Kornmeier
TAGS: albinism, motion, motion perception, perception, pathologic nystagmus
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):39. https://doi.org/10.1167/iovs.64.14.39

Includes: Supplemental Content

Glaucoma November 2023

Spatial Summation in the Glaucomatous Macula: A Link With Retinal Ganglion Cell Damage

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Giovanni Montesano; Tony Redmond; Pádraig J. Mulholland; David F. Garway-Heath; Giovanni Ometto; Dario Romano; Federica Antonacci; Lucia Tanga; Carmela Carnevale; Luca M. Rossetti; David P. Crabb; Francesco Oddone
TAGS: glaucoma, spatial summation, macula lutea, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):36. https://doi.org/10.1167/iovs.64.14.36

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology November 2023

Study in Patients With Unilateral Horner Syndrome Supports the Role of Müller's Muscle in the Eyelid-Dark Reflex

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Mattan Arazi; Ari Leshno; Noa Sussman; Lital Smadar; Ruth Huna-Baron; Oded Sagiv
TAGS: eyelid, horner syndrome, muscle, reflex
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):35. https://doi.org/10.1167/iovs.64.14.35

Glaucoma November 2023

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

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Simon T. Gustavsson; Tim J. Enz; James R. Tribble; Mattias Nilsson; Anna Lindqvist; Christina Lindén; Anna Hagström; Carola Rutigliani; Emma Lardner; Gustav Stålhammar; Pete A. Williams; Gauti Jóhannesson
TAGS: glaucoma, niacinamide, ocular hypertension, retinal vasculature, vasculature, vascular flow, eye, optic disk
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):34. https://doi.org/10.1167/iovs.64.14.34

Includes: Supplemental Content

Artificial Intelligence November 2023

AI-Based Decision-Support System for Diagnosing Acanthamoeba Keratitis Using In Vivo Confocal Microscopy Images

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Alisa Lincke; Jenny Roth; António Filipe Macedo; Patrick Bergman; Welf Löwe; Neil S. Lagali
TAGS: acanthamoeba keratitis, cornea, cysts, datasets, microscopy, confocal, training, deep learning, artifacts
Trans. Vis. Sci. Tech.. 2023; 12(11):29. https://doi.org/10.1167/tvst.12.11.29

Retina November 2023

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

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Eric C. Spivey; Jinggang Yin; Edward Chaum; John P. Wikswo
TAGS: retinal pigment cell, vascular endothelial growth factor a, fluid flow, bodily secretions, hypoxia
Trans. Vis. Sci. Tech.. 2023; 12(11):28. https://doi.org/10.1167/tvst.12.11.28

Includes: Supplemental Content

Eye Movements, Strabismus, Amblyopia and Neuro-ophthalmology November 2023

How Do Most Young Moderate Hyperopes Avoid Strabismus?

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Sonisha Neupane; Vidhyapriya Sreenivasan; Yifei Wu; Clara Mestre; Katie Connolly; Don W. Lyon; T. Rowan Candy
TAGS: strabismus, visual accommodation, child, eye, finding of motor response
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):17. https://doi.org/10.1167/iovs.64.14.17

Genetics November 2023

Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals

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Perttu J. Liuska; Joel T. Rämö; Susanna Lemmelä; Kai Kaarniranta; Hannu Uusitalo; Elisa Lahtela; Mark J. Daly; Mika Harju; Aarno Palotie; Joni A. Turunen; for the FinnGen Study†
TAGS: apolipoprotein e, eye diseases, glaucoma, haplotypes, apolipoprotein e genotype, alleles, genotype
Invest. Ophthalmol. Vis. Sci.. 2023; 64(14):33. https://doi.org/10.1167/iovs.64.14.33

Includes: Supplemental Content

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Too Much of a Good Thing: Extended Duration of Gut Microbiota Depletion Reverses Protection From Experimental Autoimmune Uveitis

Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes

Investigating the Spatiotemporal Summation of Perimetric Stimuli in Dry Age-Related Macular Degeneration

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

Diagnostic Potential of Anterior Segment Optical Coherence Tomography Scans for Pseudomonas Keratitis

Social Determinants of Health in Pediatric Ophthalmology Patients: Availability of Data in the Electronic Health Record and Association With Clinic Attendance

Report From the 2022 Mary Tyler Moore Vision Initiative Diabetic Retinal Disease Clinical Endpoints Workshop

Biological and Adhesive Properties of an Autologous Protein-Based Fibrin Sealant for Ophthalmological Applications

Single- and Dual-Task Gait Performance in Patients With Open-Angle Glaucoma: A Cross-sectional Study

GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion

Unique Attributes of Guinea Pigs as New Models to Study Ocular Herpes Pathophysiology and Recurrence

Essential Role of XBP1 in Maintaining Photoreceptor Synaptic Integrity in Early Diabetic Retinopathy

Altered Perception of the Bistable Motion Quartet in Albinism

Spatial Summation in the Glaucomatous Macula: A Link With Retinal Ganglion Cell Damage

Study in Patients With Unilateral Horner Syndrome Supports the Role of Müller's Muscle in the Eyelid-Dark Reflex

Nicotinamide Prevents Retinal Vascular Dropout in a Rat Model of Ocular Hypertension and Supports Ocular Blood Supply in Glaucoma Patients

AI-Based Decision-Support System for Diagnosing Acanthamoeba Keratitis Using In Vivo Confocal Microscopy Images

A Microfluidic Platform for the Time-Resolved Interrogation of Polarized Retinal Pigment Epithelial Cells

How Do Most Young Moderate Hyperopes Avoid Strabismus?

Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals

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