Cornea

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Cornea April 2024

Expression and Impact of Fibronectin, Tenascin-C, Osteopontin, and Type XIV Collagen in Fuchs Endothelial Corneal Dystrophy

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Ange Tchatchouang; Isabelle Brunette; Patrick J. Rochette; Stéphanie Proulx
TAGS: collagen, fibronectins, osteopontin, tenascin, endothelium, hereditary corneal dystrophy
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):38. https://doi.org/10.1167/iovs.65.4.38

Includes: Supplemental Content

Cornea April 2024

Mitochondrial DNA-Activated cGAS-STING Signaling in Environmental Dry Eye

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Xiying Tan; Qianqian Chen; Zhonghua Chen; Zhenzhen Sun; Wei Chen; Ruifen Wei
TAGS: dna, dna, mitochondrial, dry eye syndromes, mitochondria, signal transduction, mice, cytoplasm
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):33. https://doi.org/10.1167/iovs.65.4.33

Includes: Supplemental Content

Immunology and Microbiology April 2024

Aspergillus fumigatus Hypoxia Adaptation Is Critical for the Establishment of Fungal Keratitis

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Jorge D. Lightfoot; Emily M. Adams; Manali M. Kamath; Becca L. Wells; Kevin K. Fuller
TAGS: cornea, fungal keratitis, hypoxia, aspergillus fumigatus
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):31. https://doi.org/10.1167/iovs.65.4.31

Includes: Supplemental Content

Physiology and Pharmacology April 2024

CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

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Linyan Ma; Lingling Yang; Xiaolei Wang; Leilei Zhao; Xiaofei Bai; Xia Qi; Qing Chen; Ya Li; Qingjun Zhou
TAGS: bodily secretions, calcitonin gene-related peptide, cornea, lacrimal gland, mice, sensory nerves, trpv1 receptor, capsaicin
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):30. https://doi.org/10.1167/iovs.65.4.30

Includes: Supplemental Content

Cornea April 2024

Endoplasmic Reticulum Stress and Unfolded Protein Response in Vernal Keratoconjunctivitis

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Andrea Leonardi; Alice Donato; Umberto Rosani; Antonino Di Stefano; Fabiano Cavarzeran; Paola Brun
TAGS: conjunctiva, endoplasmic reticulum, keratoconjunctivitis, vernal, stress, unfolded protein response, apoptosis, genes, autophagy, cell culture techniques
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):23. https://doi.org/10.1167/iovs.65.4.23

Includes: Supplemental Content

Cornea April 2024

Characterization of a Novel Mouse Model for Fuchs Endothelial Corneal Dystrophy

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Subashree Murugan; Viviane Souza de Campos; Sachin Anil Ghag; Matthew Ng; Rajalekshmy Shyam
TAGS: cornea, endothelial cells, endothelium, hereditary corneal dystrophy, mice, corneal endothelium, tamoxifen, corneal edema, oxidative stress
Invest. Ophthalmol. Vis. Sci.. 2024; 65(4):18. https://doi.org/10.1167/iovs.65.4.18

Artificial Intelligence April 2024

Artificial Neural Network for Automated Keratoconus Detection Using a Combined Placido Disc and Anterior Segment Optical Coherence Tomography Topographer

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Jorge L. Alió del Barrio; Alaa M. Eldanasoury; Juan Arbelaez; Stefano Faini; Francesco Versaci
TAGS: keratoconus, optical coherence tomography
Trans. Vis. Sci. Tech.. 2024; 13(4):13. https://doi.org/10.1167/tvst.13.4.13

Includes: Supplemental Content

Cornea & External Disease April 2024

A Shape Memory Polymeric Shield for Protecting Corneal Endothelium During Phacoemulsification

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Yinan Liu; Yuqi Li; Jing Ji; Yubo Fan; Jing Hong; Lizhen Wang
TAGS: cornea, corneal endothelium, endothelium, memory, phacoemulsification, polymers, shape, surgical procedures, operative, trypan blue, body temperature
Trans. Vis. Sci. Tech.. 2024; 13(4):11. https://doi.org/10.1167/tvst.13.4.11

Clinical and Epidemiologic Research March 2024

Macular Curvature in Adults Born Preterm With and Without ROP: Results from the Gutenberg Prematurity Eye Study

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Achim Fieß; Christin Volmering; Sandra Gißler; Eva Mildenberger; Michael S. Urschitz; Panagiotis Laspas; Bernhard Stoffelns; Norbert Pfeiffer; Alexander K. Schuster
TAGS: adult, eye, infant, premature, premature birth, perinatal period, birth weight, medical history
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):39. https://doi.org/10.1167/iovs.65.3.39

Includes: Supplemental Content

Cornea March 2024

Lack of Elevated Expression of TGFβ3 Contributes to the Delay of Epithelial Wound Healing in Diabetic Corneas

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Nan Gao; Fu-Shin Yu
TAGS: cornea, diabetes mellitus, epithelium, protein isoforms, wound healing, wounds and injuries, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):35. https://doi.org/10.1167/iovs.65.3.35

Cornea March 2024

Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity

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Seungwoon Seo; Seong Keun Sonn; Hyae Yon Kweon; Jing Jin; Tsutomu Kume; Je Yeong Ko; Jong Hoon Park; Goo Taeg Oh
TAGS: cilia, cornea, mice, neural crest cells, corneal stroma
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):30. https://doi.org/10.1167/iovs.65.3.30

Includes: Supplemental Content

Cornea March 2024

Diabetic Ocular Surface Has Defects in Oxygen Uptake Revealed by Optic Fiber Microsensor

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Sun Qin; Li Ma; Fernando Ferreira; Chelsea Brown; Manuel F. Navedo; Brian Reid; Min Zhao
TAGS: cornea, diabetes mellitus, ocular surfaces, oxygen, optics
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):27. https://doi.org/10.1167/iovs.65.3.27

Immunology and Microbiology March 2024

Whole Genome Sequencing Highlights the Pathogenic Profile in Nocardia Keratitis

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Xiaoyan Guo; Zijun Zhang; Qiankun Chen; Leying Wang; Xizhan Xu; Zhenyu Wei; Yang Zhang; Kexin Chen; Zhiqun Wang; Xinxin Lu; Qingfeng Liang
TAGS: cornea, genes, keratitis, nocardia, family
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):26. https://doi.org/10.1167/iovs.65.3.26

Includes: Supplemental Content

Cornea March 2024

Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial Cells

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Fang Zheng; Jingjing Su; Jiaoman Wang; Qing Zhan; Mei Su; Sicheng Ding; Wei Li; Ying-Ting Zhu; Ping Guo
TAGS: abca1 gene, body tissue, epithelial cells, eyelid, meibomian gland, membrane transport proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):24. https://doi.org/10.1167/iovs.65.3.24

Cornea March 2024

Persistence of Contact Lens-Induced Corneal Parainflammation Following Lens Removal

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Ananya Datta; Ji Hyun Lee; Tiffany Truong; Orneika Flandrin; Yujia Yang; David J. Evans; Suzanne M. J. Fleiszig
TAGS: cornea, lens (device), lens, crystalline, persistence, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):8. https://doi.org/10.1167/iovs.65.3.8

Includes: Supplemental Content

Immunology and Microbiology March 2024

Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies

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Satyashree Gagan; Agimanailiu Khapuinamai; Divya Kapoor; Pankaj Sharma; Tejabhiram Yadavalli; Joveeta Joseph; Deepak Shukla; Bhupesh Bagga
TAGS: heparanase, herpes simplex infection, human herpesvirus 1, keratitis, mice, mice, inbred c57bl, viruses, simplexvirus, animal testing
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):7. https://doi.org/10.1167/iovs.65.3.7

Includes: Supplemental Content

Cornea March 2024

Substrate Stiffness Modulates Stemness and Differentiation of Rabbit Corneal Endothelium Through the Paxillin–YAP Pathway

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Shuting Liu; Hua Chen; Huatao Xie; Xin Liu; Mingchang Zhang
TAGS: chronic exertional compartment syndrome, cornea, corneal endothelium, oryctolagus cuniculus, scirrhous adenocarcinoma
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):15. https://doi.org/10.1167/iovs.65.3.15

Includes: Supplemental Content

Cornea March 2024

NEAT1 Deficiency Promotes Corneal Epithelial Wound Healing by Activating cAMP Signaling Pathway

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Tian Sang; Yani Wang; Zhiqing Wang; Di Sun; Shengqian Dou; Yaoyao Yu; Xiaoyun Wang; Can Zhao; Qun Wang
TAGS: cornea, cyclic amp, epithelium, signal pathway, signal transduction pathways, wound healing, mice, inflammation
Invest. Ophthalmol. Vis. Sci.. 2024; 65(3):10. https://doi.org/10.1167/iovs.65.3.10

Includes: Supplemental Content

Cornea February 2024

Ferroptosis as a Potential Therapeutic Target for Reducing Inflammation and Corneal Scarring in Bacterial Keratitis

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Qiankun Chen; Leying Wang; Yuan Wei; Xizhan Xu; Xiaoyan Guo; Qingfeng Liang
TAGS: bacterial keratitis, cicatrix, cornea, ferroptosis, inflammation, mice, iron
Invest. Ophthalmol. Vis. Sci.. 2024; 65(2):29. https://doi.org/10.1167/iovs.65.2.29

Includes: Supplemental Content

Cornea & External Disease February 2024

In Vivo Evaluation of Corneal Biomechanics Following Cross-Linking Surgeries Using Optical Coherence Elastography in a Rabbit Model of Keratoconus

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Yanzhi Zhao; Yirui Zhu; Yange Yan; Hongwei Yang; Jingchao Liu; Yongan Lu; Yingjie Li; Guofu Huang
TAGS: biomechanics, cornea, cross-linking, elasticity imaging techniques, keratoconus, optics, oryctolagus cuniculus, surgical procedures, operative, corneal collagen cross-linking, atrial myxoma with lentigines
Trans. Vis. Sci. Tech.. 2024; 13(2):15. https://doi.org/10.1167/tvst.13.2.15

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Expression and Impact of Fibronectin, Tenascin-C, Osteopontin, and Type XIV Collagen in Fuchs Endothelial Corneal Dystrophy

Mitochondrial DNA-Activated cGAS-STING Signaling in Environmental Dry Eye

Aspergillus fumigatus Hypoxia Adaptation Is Critical for the Establishment of Fungal Keratitis

CGRP Released by Corneal Sensory Nerve Maintains Tear Secretion of the Lacrimal Gland

Endoplasmic Reticulum Stress and Unfolded Protein Response in Vernal Keratoconjunctivitis

Characterization of a Novel Mouse Model for Fuchs Endothelial Corneal Dystrophy

Artificial Neural Network for Automated Keratoconus Detection Using a Combined Placido Disc and Anterior Segment Optical Coherence Tomography Topographer

A Shape Memory Polymeric Shield for Protecting Corneal Endothelium During Phacoemulsification

Macular Curvature in Adults Born Preterm With and Without ROP: Results from the Gutenberg Prematurity Eye Study

Lack of Elevated Expression of TGFβ3 Contributes to the Delay of Epithelial Wound Healing in Diabetic Corneas

Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity

Diabetic Ocular Surface Has Defects in Oxygen Uptake Revealed by Optic Fiber Microsensor

Whole Genome Sequencing Highlights the Pathogenic Profile in Nocardia Keratitis

Expression of ATP-Binding Cassette Transporter A1 (ABCA1) in Eyelid Tissues and Meibomian Gland Epithelial Cells

Persistence of Contact Lens-Induced Corneal Parainflammation Following Lens Removal

Exploring Heparanase Levels in Tears: Insights From Herpes Simplex Virus-1 Keratitis Patients and Animal Studies

Substrate Stiffness Modulates Stemness and Differentiation of Rabbit Corneal Endothelium Through the Paxillin–YAP Pathway

NEAT1 Deficiency Promotes Corneal Epithelial Wound Healing by Activating cAMP Signaling Pathway

Ferroptosis as a Potential Therapeutic Target for Reducing Inflammation and Corneal Scarring in Bacterial Keratitis

In Vivo Evaluation of Corneal Biomechanics Following Cross-Linking Surgeries Using Optical Coherence Elastography in a Rabbit Model of Keratoconus

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